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Lipids: DHA and ARA

These special nutrients can provide benefits to infant mental and visual development

DHA and ARA occur naturally in breast milk and belong to a class of nutrients called "lipids", or "fats". Lipids are an essential part of a healthy diet because they are important structural components of vital organs, particularly an infant's brain and eyes.

Interest in DHA and ARA has increased following several scientific studies showing that infants fed formula supplemented with DHA and ARA gained intellectual and visual benefits not found in infants fed standard formulas without DHA and ARA.

In addition, recent research has also demonstrated that DHA and ARA's benefits may extend beyond advantages in infant mental and visual development.

Brain & Eye Development


Lipids, in general, are important components of the nervous system and DHA and ARA, in specific, are major constituents of an infant's brain and retinal portion of the eyes. The retina is that part of the eye that transmits images to the brain and is necessary for normal vision. Forty percent of the retina's lipid content is DHA.

Given the important structural role that DHA and ARA play and the rapid growth of the brain in infancy, it is essential that an infant have an ample supply of DHA and ARA.

Sources of DHA


Prior to birth, infants receive maternal DHA and ARA across the placenta. After birth, breastfed infants continue to receive maternal DHA and ARA from breast milk. Researchers believe formula-fed infants should receive these nutrients from lipid-fortified formulas until they start solid foods in the second half of the first year. (Foods high in DHA include meat, fish and eggs. Consult your pediatrician about an appropriate age to give solid foods.)

In the United States prior to 2002, DHA and ARA were not added to formulas. It was thought that infants could synthesize adequate amounts of DHA and ARA from vegetable oils in formula. However, it is now known that many formula-fed infants have lower levels of DHA and ARA than breast-fed infants. Researchers now believe that many infants cannot make sufficient amounts of DHA and ARA from the vegetable oils and unless DHA and ARA are added directly to formula, researchers contend, formula-fed infants will not receive adequate amounts of these lipids.

Bright Beginnings milk-based formula provides DHA and ARA in amounts that have been proven to produce lipid levels in infants similar to those observed in breast-fed infants.

The DHA and ARA in Bright Beginnings are from vegetable sources - the only source which has been recognized as "safe" for inclusion in infant formulas by the Food and Drug Administration.

Clinical Studies With DHA

Long term benefits of DHA and ARA in breast milk

  • In a study published in the journal Pediatrics which examined early diet and later cognitive performance, researchers found that breastfeeding was associated with increases in cognitive ability and school performance. (1)
  • Researchers attributed these increases to effects of lipids, especially DHA, on early neurodevelopment. Researchers in England found that women who regularly ate oily fish (a source of DHA) throughout their pregnancy and during lactation gave birth to children who had better visual development at the age of three compared to those children of mothers with similar diets who did not breast feed. (2)

Long term cognitive and visual benefits of DHA and ARA supplemented infant formula

  • Infants fed formula supplemented with DHA and ARA for the first 4 months of life had problem-solving skills at 10 months of age that were superior to those of infants fed a formula without DHA and ARA. Higher problem solving skills in infancy are associated with higher performance on tests of IQ in childhood. (3)
  • In a study funded by the National Institutes of Health comparing lipid-enriched formula to unsupplemented formula, DHA and ARA-enriched formula fed during the first 4 months of life was shown to significantly improve IQ scores at the age of 18 months. (4) Infants fed lipid-enriched formula also had better visual acuity at 4 months and 1 year as compared to those who were fed unsupplemented formula. The visual acuity of the supplemented group was similar to that of breastfed infants. (5)

Expert Opinions On DHA


Numerous groups of nutrition experts have recommended the addition of DHA and ARA to infant formulas, including:

  • A World Health Organization and United Nations Food and Agricultural Organization (WHO/FAO) panel
  • The British Nutrition Foundation
  • A Child Health Foundation-sponsored panel
  • A National Institutes of Health and International Society for the study of Fats and Lipids (NIH/ISSFAL)-sponsored workshop

1. Horwood, LJ and Ferguson, DM. Breastfeeding and Later Cognitive and Academic Outcomes, Pediatrics 101(1):1-7, 1998. EE, Emmett, PM et al. Stereoacuity at Age 3.5 Years in Children Born Full Term is Associated with Prenatal and Postnatal Dietary Factors: A Report From a Population Based Cohort Study, Am J Clin Nutr 73:316-322, 2001
3. Willatts, P, Forstyh, JS, DiModugno, MK et al. Effects of Long-Chain Polyunsaturated Fatty Acids in Infant Formula on Problem Solving at 10 Months of Age, Lancet 352:688-691, 1998.
4. Birch, EE, Garfield, S, Hoffman, DR et al. A Randomized Controlled Trail of Early Dietary Supply of Long-Chain Polyunsaturated Fatty Acids and Mental Development in Term Infants, Develop Med Child Neurol 42: 174-181, 2000
5. Birch, EE, Hoffman, DR, Uauy, R et al. Visual Acuity and the Essentiality of Docosahexanoic Acid and Arachidonic Acid in the Diets of Term infants, Pediatr Res 44:201-209, 1998.


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